應用文集

The Evosep One enables the analysis of large sample cohorts in a rapid, reproducible, and robust manner. The Evotip is the key feature of this technology, as it simplifies sample preparation by seamlessly integrating desalting – which is typically required in bottom-up proteomics workflows – with LC-MS sample introduction. It is a high precision and well characterized technology with a loading capacity of 1 ug. The Evosep One partially elutes peptides from the Evotip while retaining other large and more hydrophobic molecules that are discarded with the single-use, disposable Evotip. This methodology ensures high system robustness, excellent run-to-run reproducibility, and completely eliminates carryo ver from the injection system. Altogether, this enables the Evosep to easily switch between different routine analyses without compromising analysis quality. Finally, storage of samples before LC-MS analysis is typically done in tubes, plates, or HPLC vials, resulting in sample losses due to additional sample transfer steps and peptide adsorbance to plastics. In comparison, the Evotip is an integrated part of the workflow, reducing the sample transfer steps, resulting in less exposure of peptides to plastic surfaces once loaded and immobilized on the Evotip…….